There is no information available concerning the treatment of overdosage. There is no specific antidote. In general, overdosage would be expected to produce effects that are an extension of common adverse effects or of the serious metabolic sequelae observed. Treatment should be symptomatic and supportive. Neither peritoneal dialysis nor haemodialysis appear to remove the drug rapidly enough to cause a precipitous decline in the plasma concentration of pentamidine isethionate.
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